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ARA - 290 · 16mg
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99%+ HPLC Purity — Independently verified by accredited US laboratory -
Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
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GMP-Certified Manufacturing — USA facility, ISO 9001:2015
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Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
4.9 847 verified reviews
ARA - 290 · 16mg
Total Price
$949.90
Discounted Price
$550.94
Vials
10 vials
You Save
$398.96
42% OFF
Select Strength (mg)
99% HPLC Purity
Select Vials
Bulk pricing applied
📈 Upgrade to 10 vials and save an extra vs. buying 5 — nearly 3 free vials.
Select Purchase Option:
-
99%+ HPLC Purity —
Independently verified by accredited US laboratory
-
Endotoxin-Screened —
LAL tested, LPS-free, endotoxin report available
-
GMP-Certified Manufacturing —
USA facility, ISO 9001:2015
-
Lyophilized for Stability —
Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from the erythropoietin (EPO) sequence. It is used in laboratory research as a selective ligand for the innate repair receptor (IRR), a heteromeric receptor complex composed of the erythropoietin receptor and the β-common receptor. It is supplied strictly for laboratory research use only and is not approved or intended for human or animal use, ingestion, dosing, or therapeutic application.
Published research context
In the peer-reviewed literature the IRR is described as being expressed at low levels under baseline conditions and upregulated in experimental models of tissue stress, inflammation, or ischemia. Published in-vitro and animal-model studies have characterised IRR activation in relation to:
• Inflammatory signalling cascades
• Cytokine expression profiles
• Apoptotic and oxidative-stress markers
• Tissue-remodelling and regeneration models
• Neuronal-signalling models
Published work also reports that cibinetide does not substantially activate the homodimeric erythropoietin receptor associated with erythropoiesis, which is why it is frequently used as a comparator to EPO in receptor-selectivity experiments.
These descriptions summarise published experimental observations only and are provided for scientific context. They must not be interpreted as claims of therapeutic, diagnostic, or clinical benefit.
This product is intended strictly for research and laboratory use only. Not for human or animal use. No statement on this page describes or implies any physiological, cosmetic, diagnostic, or therapeutic effect in humans or animals.
ARA-290 at a glance
| Application | Research use only |
|---|
What is ARA-290?
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a receptor complex involved in tissue protection, anti-inflammatory signaling, and cellular repair. Unlike EPO, cibinetide does not significantly stimulate red blood cell production, a difference examined in preclinical receptor-selectivity studies.
Why is ARA-290 studied?
The peptide is studied because it separates two activities that are combined in the parent protein. Erythropoietin signals through both the classical homodimeric receptor and a distinct heteromeric receptor complex; short helix-B-derived peptides bind the latter selectively, which makes them useful probes for isolating that pathway in experimental systems.2
How is ARA-290 studied in the lab?
Reported work uses rodent injury models and cultured cells, with readouts including receptor binding, cell survival under stress, and reticulocyte or haematocrit measurements used as negative controls to confirm the absence of erythropoietic signalling.1, 2
What has preclinical research reported?
Non-erythropoietic design (in vitro and rodent)
Peptides derived from the tertiary structure of erythropoietin were reported to retain tissue-protective signalling in rodent models while producing no measurable erythropoietic response.1
Receptor pharmacology
Review work describes the heteromeric receptor complex through which helix-B-derived peptides are proposed to act, distinguishing it from the homodimeric receptor that drives red-cell production.2
Forms studied and handling
Supplied as a lyophilised powder in a sealed vial. Published handling practice for research peptides of this class is cold, dry, light-protected storage of the lyophilised solid, with reconstituted material kept refrigerated and used within the stability window established by the laboratory. For laboratory research use only.
References
- Brines M, Patel NSA, Villa P, et al. Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin. Proc Natl Acad Sci U S A. 2008;105(31):10925-10930. doi:10.1073/pnas.0805594105
- Brines M, Cerami A. Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response. J Intern Med. 2008;264(5):405-432. doi:10.1111/j.1365-2796.2008.02024.x
For laboratory research use only. Products on this website are intended solely for in-vitro research. They are not medicines, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. Any administration to humans or animals is strictly prohibited.
What are these peptides made for?
Our peptides are produced exclusively for laboratory and scientific research purposes.
Licensed Peptides™ products are developed using industry-standard synthesis and purification protocols, making them suitable for in vitro research, analytical testing, and experimental models.
Research-grade standards
- Synthesized via Solid Phase Peptide Synthesis (SPPS)
- Purified using advanced HPLC methods
- Verified through analytical quality control processes
- Screened for heavy metals and endotoxins
Consistency across batches
Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments.
Applications
Our peptides are commonly used in research involving:
- Cellular signaling pathways
- Tissue remodeling and repair mechanisms
- Extracellular matrix regulation
- Molecular biology and biochemical studies
All products are intended for research use only and are not for human or animal consumption, therapeutic use, or clinical application.
Why buy from Licensed Peptides
At Licensed Peptides™, quality isn’t a claim — it’s a controlled, repeatable process.
Every peptide we produce follows a strict, pharma-grade workflow designed to ensure purity, stability, and consistency from synthesis to delivery.
What sets us apart
ISO-certified cleanroom manufacturing
All peptides are synthesized in sterile, controlled environments to eliminate contamination risk and ensure batch consistency.
>99% verified purity (HPLC tested)
We use advanced High-Performance Liquid Chromatography (HPLC) to separate and verify peptide purity with precision.
Comprehensive safety testing
Each batch undergoes heavy metal and endotoxin screening to ensure it is free from hidden contaminants.
Pharma-grade raw materials
We start with rigorously tested amino acids and reagents, ensuring integrity at the molecular level.
Lyophilized for stability
Freeze-dried peptides maintain long-term stability, potency, and reliability for research applications.
Nitrogen-sealed vials
Every vial is protected from oxygen and moisture, preserving structural integrity during storage and transit.
Built for serious research
From synthesis to delivery, every step is engineered to meet the expectations of professionals who require accuracy, consistency, and reliability.
For laboratory research use only. Not for human or veterinary use.
How orders ship
We understand that timing and product integrity are critical for research.
| Ships to | United States (including minor outlying islands) |
|---|---|
| Processing days | Monday to Friday, excluding holidays |
| Daily cut-off | Paid orders placed before 4:00 PM PST are typically shipped the same business day |
| Free shipping | FedEx 2-Day Express on orders over $200 and for VIP members |
| Standard | USPS Ground Advantage, 3–7 business days (not guaranteed) — $8.95 |
| Expedited | FedEx 2-Day $11.95 · UPS 2-Day $19.95 · FedEx Next Day $44.99 |
| Signature | Required on delivery for orders of $1,000 or more |
How orders are handled
Cold chain protection
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity.
Secure & protective packaging
Each order is carefully packed to protect against temperature fluctuations, moisture exposure, and physical damage during transit.
Tracking
Once your order has shipped you will receive a tracking number by email, so you can monitor delivery progress.
Shipped from the United States
Orders are dispatched domestically from a U.S.-based operation, so there are no international customs steps.
Delivery times
Shipping times are estimates and begin after order processing. Delays may occur due to carrier issues, weather, or other unforeseen factors, and delivery dates are not guaranteed. Full terms are in our Shipping & Delivery Policy.
For laboratory research use only. Not for human or veterinary use.
Additional information
| pack | 1 pack, 3 pack, 5 pack, 10 pack |
|---|
Storage conditions at a glance
| Lyophilized, in transit | Stable for shipping for up to 3–4 months |
|---|---|
| Lyophilized, short term | Room temperature is usually adequate for several weeks; refrigeration under 4°C (39°F) is generally acceptable |
| Lyophilized, long term | Freezer at -80°C (-112°F) for several months to years |
| After reconstitution | Refrigerated; stable for up to 30 days |
| Light and moisture | Keep cold and away from light in the original sealed vial |
Why the powder is stable
All of our products are manufactured using the lyophilization (freeze drying) process, which keeps them stable for shipping for up to 3–4 months.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until it is reconstituted with bacteriostatic water.
Storing vials on arrival
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used in the next several days, weeks or months, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
For longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80°C (-112°F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
After reconstitution
Once the peptides are reconstituted with bacteriostatic water, they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
For laboratory research use only. Not for human or veterinary use.
99%+ — Passes ≥99% 
99%+ Every Batch
Often Not Disclosed
