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5-Amino-1MQ Capsules · 50mg
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99%+ HPLC Purity — Independently verified by accredited US laboratory -
Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
-
GMP-Certified Manufacturing — USA facility, ISO 9001:2015
-
Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
4.9 847 verified reviews
5-Amino-1MQ Capsules · 50mg
Total Price
$947.99
Discounted Price
$729.95
Packs
5 packs
You Save
$218.04
23% OFF
Select Strength (mg)
99% HPLC Purity
Select Packs
Bulk pricing applied
📈 Upgrade to 10 vials and save an extra vs. buying 5 — nearly 3 free vials.
Select Purchase Option:
-
99%+ HPLC Purity —
Independently verified by accredited US laboratory
-
Endotoxin-Screened —
LAL tested, LPS-free, endotoxin report available
-
GMP-Certified Manufacturing —
USA facility, ISO 9001:2015
-
Lyophilized for Stability —
Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
60 Capsules
Capsule form for precise research.
5-Amino-1MQ Capsules 50mg are supplied strictly for laboratory research use only. This material is intended for analytical and controlled research applications. It is not approved or intended for human or animal use, ingestion, dosing, or therapeutic application.
Within controlled laboratory settings, 5-Amino-1MQ is utilized to study how NNMT inhibition alters intracellular nicotinamide handling and affects downstream metabolic signaling pathways, including those related to NAD+ homeostasis, mitochondrial dynamics, and adipocyte functionality. Investigators value this compound due to its specificity, stability, and consistent behavior in experimental models.
This product is supplied as a high-purity research compound and is manufactured to meet stringent quality standards, including LPS-free and endotoxin-free specifications. Each batch undergoes research peptide endotoxin testing to ensure suitability for sensitive laboratory applications where contamination control is critical.
5-Amino-1MQ at a glance
| Molecular formula | C₁₀H₁₁N₂ |
|---|---|
| Molecular weight | 159.21 g/mol |
| CAS number | 42464-96-0 |
| PubChem CID | 950107 |
| Form supplied | Lyophilized powder |
| Purity | Research-grade, high-purity standard |
| Application | Research use only |
What is 5-Amino-1MQ?
5-Amino-1MQ is a research material used in laboratory studies of NNMT-related pathways, nicotinamide metabolism, and experimental cellular signaling. Any references to biological activity are provided strictly for research context and must not be interpreted as claims of safety, efficacy, or intended human use.
Why is 5-Amino-1MQ studied?
Nicotinamide N-methyltransferase (NNMT) transfers a methyl group from S-adenosylmethionine to nicotinamide, diverting nicotinamide away from NAD+ salvage. That position at the junction of two pathways is why selective, membrane-permeable NNMT inhibitors were developed as chemical probes.3
How is 5-Amino-1MQ studied in the lab?
In controlled laboratory settings, 5-Amino-1MQ may be used to investigate how NNMT modulation affects NAD+ availability, redox balance, and related metabolic pathways. This product is supplied for research purposes only and is not offered for human or veterinary use.
Reported laboratory work in this series measured NNMT enzyme activity and 1-methylnicotinamide output in cells, confirmed membrane permeability, and then tracked adipose-tissue and metabolic readouts in diet-induced obese mice.3
What has preclinical research reported?
Key Research Attributes
- Highly specific NNMT inhibition profile
- Small-molecule stability and consistency
- Suitable for metabolic and enzymatic pathway modeling
- Compatible with NAD+-focused experimental designs
- Non-hormonal mechanism of action
Research Applications
5-Amino-1MQ is frequently used in academic and private laboratory research related to:
- Metabolic regulation pathways
- Obesity and adiposity models (non-clinical)
- Energy expenditure signaling
- NAD+ salvage mechanisms
- Mitochondrial efficiency and redox balance
- Cellular aging and stress response modeling
- Inflammation-associated metabolic pathway exploration
Research Context
References to obesity, adipose tissue, mitochondrial function, or glucose-related pathways on this page are provided for laboratory research context only. They do not imply therapeutic, diagnostic, or clinical benefit.
Selective NNMT inhibition in mice
Neelakantan and colleagues reported that selective, membrane-permeable small-molecule NNMT inhibitors reversed diet-induced obesity in a mouse model, with corresponding changes in adipose tissue.3
Forms studied and handling
- Store in a cool, dry location away from direct light
- Maintain appropriate laboratory storage protocols
- Reconstituted material should be handled under sterile research conditions
- Stability is preserved when stored according to standard laboratory guidelines
References
- Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H. Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction. Diabetes Obes Metab. 2024 Nov;26(11):5272-5282. doi: 10.1111/dom.15879. Epub 2024 Aug 19. PMID: 39161060; PMCID: PMC11622326. PMID 39161060
- Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism. PMID 16227617
- Neelakantan H, Vance V, Wetzel MD, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochem Pharmacol. 2018;147:141–152. doi:10.1016/j.bcp.2017.11.007
For laboratory research use only. Products on this website are intended solely for in-vitro research. They are not medicines, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. Any administration to humans or animals is strictly prohibited.
What are these peptides made for?
Our peptides are produced exclusively for laboratory and scientific research purposes.
Licensed Peptides™ products are developed using industry-standard synthesis and purification protocols, making them suitable for in vitro research, analytical testing, and experimental models.
Research-grade standards
- Synthesized via Solid Phase Peptide Synthesis (SPPS)
- Purified using advanced HPLC methods
- Verified through analytical quality control processes
- Screened for heavy metals and endotoxins
Consistency across batches
Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments.
Applications
Our peptides are commonly used in research involving:
- Cellular signaling pathways
- Tissue remodeling and repair mechanisms
- Extracellular matrix regulation
- Molecular biology and biochemical studies
All products are intended for research use only and are not for human or animal consumption, therapeutic use, or clinical application.
Why buy from Licensed Peptides
At Licensed Peptides™, quality isn’t a claim — it’s a controlled, repeatable process.
Every peptide we produce follows a strict, pharma-grade workflow designed to ensure purity, stability, and consistency from synthesis to delivery.
What sets us apart
ISO-certified cleanroom manufacturing
All peptides are synthesized in sterile, controlled environments to eliminate contamination risk and ensure batch consistency.
>99% verified purity (HPLC tested)
We use advanced High-Performance Liquid Chromatography (HPLC) to separate and verify peptide purity with precision.
Comprehensive safety testing
Each batch undergoes heavy metal and endotoxin screening to ensure it is free from hidden contaminants.
Pharma-grade raw materials
We start with rigorously tested amino acids and reagents, ensuring integrity at the molecular level.
Lyophilized for stability
Freeze-dried peptides maintain long-term stability, potency, and reliability for research applications.
Nitrogen-sealed vials
Every vial is protected from oxygen and moisture, preserving structural integrity during storage and transit.
Built for serious research
From synthesis to delivery, every step is engineered to meet the expectations of professionals who require accuracy, consistency, and reliability.
For laboratory research use only. Not for human or veterinary use.
How orders ship
We understand that timing and product integrity are critical for research.
| Ships to | United States (including minor outlying islands) |
|---|---|
| Processing days | Monday to Friday, excluding holidays |
| Daily cut-off | Paid orders placed before 4:00 PM PST are typically shipped the same business day |
| Free shipping | FedEx 2-Day Express on orders over $200 and for VIP members |
| Standard | USPS Ground Advantage, 3–7 business days (not guaranteed) — $8.95 |
| Expedited | FedEx 2-Day $11.95 · UPS 2-Day $19.95 · FedEx Next Day $44.99 |
| Signature | Required on delivery for orders of $1,000 or more |
How orders are handled
Cold chain protection
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity.
Secure & protective packaging
Each order is carefully packed to protect against temperature fluctuations, moisture exposure, and physical damage during transit.
Tracking
Once your order has shipped you will receive a tracking number by email, so you can monitor delivery progress.
Shipped from the United States
Orders are dispatched domestically from a U.S.-based operation, so there are no international customs steps.
Delivery times
Shipping times are estimates and begin after order processing. Delays may occur due to carrier issues, weather, or other unforeseen factors, and delivery dates are not guaranteed. Full terms are in our Shipping & Delivery Policy.
For laboratory research use only. Not for human or veterinary use.
Additional information
| pack | 1 pack, 3 pack, 5 pack, 10 pack |
|---|
Storage
Store sealed in original packaging in a cool, dry place away from light. Do not ingest, inject, reconstitute, or otherwise administer.
99%+ — Passes ≥99% 
Download Full COA / HPLC Report (PDF) 
99%+ Every Batch
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