99%+ Purity
Guaranteed per batch
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a receptor complex involved in tissue protection, anti-inflammatory signaling, and cellular repair. Unlike EPO, cibinetide does not significantly stimulate red blood cell production, allowing it to provide tissue-protective effects without the hematologic risks associated with erythropoietin therapy.
"Cibinetide exerts its biological effects through selective binding to the innate repair receptor, a heteromeric receptor complex composed of the erythropoietin receptor and the β-common receptor. This receptor is generally expressed at low levels under normal conditions but becomes upregulated in response to tissue injury, inflammation, ischemia, or cellular stress.
Activation of the IRR initiates intracellular signaling pathways that:
• Suppress excessive inflammatory responses.
• Reduce the production of pro-inflammatory cytokines.
• Protect cells from apoptosis and oxidative stress.
• Promote tissue repair and regeneration.
• Support nerve function and recovery following injury.
Importantly, cibinetide does not substantially activate the homodimeric erythropoietin receptor responsible for red blood cell production. As a result, it can deliver tissue-protective and anti-inflammatory benefits without causing significant increases in hematocrit or hemoglobin levels."
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a receptor complex involved in tissue protection, anti-inflammatory signaling, and cellular repair. Unlike EPO, cibinetide does not significantly stimulate red blood cell production, allowing it to provide tissue-protective effects without the hematologic risks associated with erythropoietin therapy.
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products available on this website are intended solely for in-vitro research purposes (Latin: “in glass”), meaning they are used in experiments conducted outside a living organism. These products are not medicines or drugs, have not been evaluated or approved by the U.S. Food and Drug Administration (FDA), and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Any administration to humans or animals, whether by ingestion, injection, or other means, is strictly prohibited by law.
Our peptides are produced exclusively for laboratory and scientific research purposes.
Licensed Peptides™ products are developed using industry-standard synthesis and purification protocols, making them suitable for in vitro research, analytical testing, and experimental models.
Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments.
Our peptides are commonly used in research involving:
All products are intended for research use only and are not for human or animal consumption, therapeutic use, or clinical application.
At Licensed Peptides™, quality isn’t a claim. it’s a controlled, repeatable process.
Every peptide we produce follows a strict, pharma-grade workflow designed to ensure purity, stability, and consistency from synthesis to delivery.
All peptides are synthesized in sterile, controlled environments to eliminate contamination risk and ensure batch consistency.
We use advanced High-Performance Liquid Chromatography (HPLC) to separate and verify peptide purity with precision.
Each batch undergoes heavy metal and endotoxin screening to ensure it is free from hidden contaminants.
We start with rigorously tested amino acids and reagents, ensuring integrity at the molecular level.
Freeze-dried peptides maintain long-term stability, potency, and reliability for research applications.
Every vial is protected from oxygen and moisture, preserving structural integrity during storage and transit.
From synthesis to delivery, every step is engineered to meet the expectations of professionals who require accuracy, consistency, and reliability.
We understand that timing and product integrity are critical for research.
All in-stock orders placed before our daily cutoff are shipped the same day from within the United States.
We use expedited carriers to ensure your peptides arrive quickly and reliably nationwide.
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity.
Each order is carefully packed to protect against temperature fluctuations, moisture exposure, and physical damage during transit.
You’ll receive tracking information immediately upon shipment so you can monitor delivery progress.
No long international delays, no customs issues. Just fast, dependable delivery from a U.S.-based operation.
| pack | 1 pack, 3 pack, 5 pack, 10 pack |
|---|
Storage Instructions:
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
For further information on proper storage techniques, click the link below:
Peptide Storage
ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a receptor complex involved in tissue protection, anti-inflammatory signaling, and cellular repair. Unlike EPO, cibinetide does not significantly stimulate red blood cell production, allowing it to provide tissue-protective effects without the hematologic risks associated with erythropoietin therapy.
"Cibinetide exerts its biological effects through selective binding to the innate repair receptor, a heteromeric receptor complex composed of the erythropoietin receptor and the β-common receptor. This receptor is generally expressed at low levels under normal conditions but becomes upregulated in response to tissue injury, inflammation, ischemia, or cellular stress.
Activation of the IRR initiates intracellular signaling pathways that:
• Suppress excessive inflammatory responses.
• Reduce the production of pro-inflammatory cytokines.
• Protect cells from apoptosis and oxidative stress.
• Promote tissue repair and regeneration.
• Support nerve function and recovery following injury.
Importantly, cibinetide does not substantially activate the homodimeric erythropoietin receptor responsible for red blood cell production. As a result, it can deliver tissue-protective and anti-inflammatory benefits without causing significant increases in hematocrit or hemoglobin levels."
Our peptides are produced exclusively for laboratory and scientific research purposes.
Licensed Peptides™ products are developed using industry-standard synthesis and purification protocols, making them suitable for in vitro research, analytical testing, and experimental models.
Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments.
Our peptides are commonly used in research involving:
All products are intended for research use only and are not for human or animal consumption, therapeutic use, or clinical application.
At Licensed Peptides™, quality isn’t a claim. it’s a controlled, repeatable process.
Every peptide we produce follows a strict, pharma-grade workflow designed to ensure purity, stability, and consistency from synthesis to delivery.
All peptides are synthesized in sterile, controlled environments to eliminate contamination risk and ensure batch consistency.
We use advanced High-Performance Liquid Chromatography (HPLC) to separate and verify peptide purity with precision.
Each batch undergoes heavy metal and endotoxin screening to ensure it is free from hidden contaminants.
We start with rigorously tested amino acids and reagents, ensuring integrity at the molecular level.
Freeze-dried peptides maintain long-term stability, potency, and reliability for research applications.
Every vial is protected from oxygen and moisture, preserving structural integrity during storage and transit.
From synthesis to delivery, every step is engineered to meet the expectations of professionals who require accuracy, consistency, and reliability.
We understand that timing and product integrity are critical for research.
All in-stock orders placed before our daily cutoff are shipped the same day from within the United States.
We use expedited carriers to ensure your peptides arrive quickly and reliably nationwide.
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity.
Each order is carefully packed to protect against temperature fluctuations, moisture exposure, and physical damage during transit.
You’ll receive tracking information immediately upon shipment so you can monitor delivery progress.
No long international delays, no customs issues. Just fast, dependable delivery from a U.S.-based operation.
| pack | 1 pack, 3 pack, 5 pack, 10 pack |
|---|
Storage Instructions:
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
For further information on proper storage techniques, click the link below:
Peptide Storage
Guaranteed per batch
Independent lab verified
ISO/IEC 17025:2017
USA-manufactured
Free FedEx on $200+
Every batch is independently tested before it ships. Full documentation available for every product.
Not all peptide vendors hold themselves to the same verification standards.
| Verification Standard | Licensed Peptides | Generic Vendors |
|---|---|---|
| HPLC Purity Analysis | ||
| Mass Spectrometry Identity | ||
| Endotoxin Screening (LAL) | ||
| GMP-Certified USA Manufacture | ||
| COA Published & Downloadable | ||
| Same-Day USA Fulfillment |
ARA-290 is a synthetic 15–amino acid peptide based on a fragment identified in gastric proteins. It is studied exclusively in laboratory and animal-based research models.
It is commonly examined in tissue integrity studies, gastrointestinal simulations, vascular signaling experiments, inflammatory pathway research, and exploratory neurological models.
No. ARA-290 is not approved for human or veterinary medical use and is intended strictly for research and educational applications.
Preclinical research indicates it remains structurally intact in acidic and enzymatic environments, making it a reliable subject for degradation and interaction studies.
Its broad engagement with multiple biological pathways and reproducible behavior across experimental models distinguishes it from many short-chain peptides.
Human data is extremely limited. The vast majority of information comes from in-vitro and animal studies.
It is typically stored as a lyophilized powder in cool, dry conditions. Once reconstituted for experiments, storage follows standard laboratory peptide protocols.
Yes. Researchers frequently include it in combination studies to observe signaling interactions or comparative pathway behavior.
Animal studies report minimal adverse reactions, but these findings cannot be extrapolated beyond controlled research environments.
In many jurisdictions, ARA-290 can be purchased for laboratory research purposes. Regulatory requirements vary by location and should always be verified.
Some studies suggest interaction with inflammatory signaling markers in experimental models, though conclusions remain preliminary.
Its stability, versatility, and broad pathway engagement make it valuable for ongoing mechanistic research across multiple biological systems.
An LPS-free peptide indicates that the research material has been tested to ensure minimal lipopolysaccharide contamination. This is important in laboratory studies, as LPS can interfere with experimental outcomes and immune-response measurements in research models.
Endotoxins can introduce variability and confounding effects in in-vitro and laboratory experiments. An endotoxin-free peptide supports cleaner data collection and improves reproducibility in controlled research environments.
Not all peptide vendors hold themselves to the same verification standards.
99.4% HPLC Verified · Endotoxin-Screened · GMP-Certified ·
Free FedEx 2-Day on $200+
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