CJC-1295 DAC · 5mg

We supply research-grade CJC-1295 manufactured in the U.S. under strict quality control in facilities certified for Good Manufacturing Practices (GMP). Our CJC-1295 peptide is then independently verified by accredited laboratories to confirm purity, identity, sterility, and consistency. Each batch has a certificate of analysis (COA), so you can easily review the contents of your peptide and use it with confidence, knowing it’s pure and reliable.

Our certified CJC-1295 DAC meets the following manufacturing and analytical standards:

SPPS Synthesis: We supply CJC-1295 synthesized through solid-phase peptide synthesis (SPPS). This method ensures our peptides have an accurate sequence and maximum purity.

Lyophilized for Stability: Lyophilization (also called freeze-drying) helps preserve its integrity while shipping, storing, and handling in the lab.

99%+ HPLC-Verified Purity: Third-party labs test every batch of CJC-1295 to confirm purity levels of 99%+.

Identity Confirmation Through Mass Spectrometry: We confirm the peptide’s molecular identity and composition to ensure you get exactly what you order.

Heavy-Metal & Endotoxin Screening: We test each batch for bacterial endotoxins, including lipopolysaccharides (LPSs), and heavy metals. Our CJC-1295 is free of heavy metals, endotoxins, and LPSs.

Certificates of Analysis: Every batch of CJC-1295 DAC comes with transparent documentation that provides detailed analytical results.

USA GMP Manufacturing: Our CJC-1295 peptide is manufactured in GMP-certified facilities in the U.S., upholding the highest standards of quality.

Same-Day Shipping: We ship any order in stock (placed before our daily cutoff) on the same day within the US.

U.S.-Based Expert Support for Researchers: We have a responsive team that understands the needs of researchers. Contact us anytime by phone at +1 (855) 322-2214 or email [email protected] with any questions.

Proper storage is essential for preserving peptide integrity throughout laboratory investigations. Licensed Peptides supplies CJC-1295 in a lyophilized (freeze-dried) form to maximize stability during shipping and long-term storage.

Storage of CJC-1295 DAC Before Reconstitution

Store unopened vials in a cool, dry location away from direct sunlight and excessive humidity.

• For near-term laboratory use, refrigerate unopened vials below 4°C (39°F).
• For extended preservation, store unopened CJC-1295 at -20°C (-4°F) or below.

For archival storage, many laboratories utilize temperatures approaching -80°C (-112°F).

Storage of CJC-1295 After Reconstitution

Once reconstituted under laboratory conditions:

• Store below 4°C (39°F)
• Avoid repeated freeze-thaw cycles
• Keep solutions protected from contamination
• Inspect for discoloration or particulate matter before laboratory use

Here at Licensed Peptides, we supply CJC-1295 DAC for research use only. We use a 6-point verification process to ensure you receive a reliable CJC-1295 peptide that you can use for both short and long-term studies.

Our Research-Grade Standards

We understand the importance of purity and sterility in research compounds; that’s why we manufacture our CJC-1295 under strict quality standards in GMP-certified facilities, after which independent, accredited laboratories verify its quality.

Our 6-point Quality Verification Process:

• A High-Performance Liquid Chromatography (HPLC) analysis to check for 99%+ purity
• Mass spectrometry to confirm the molecular identity of each peptide and whether its sequence is accurate
• Screening for heavy metals and endotoxins, including lipopolysaccharides (LPS)
• Verification of sterility through an ISO/IEC 17025:2017-accredited laboratory
• Our team also confirms that the content (weight and concentration) is accurate
• Lastly, we physically inspect every vial for lyophilization quality, label accuracy, and overall appearance

Why Researchers Study CJC-1295 DAC

CJC-1295 is a modified analog of human growth hormone-releasing factor 1-29, or hGRF(1-29) (1-29 means it’s a chain of 29 amino acids). Researchers developed it to retain activity at the GHRH receptor while remaining detectable in circulation longer than unmodified hGRF(1-29).¹

CJC-1295 is among the most studied peptides because of its ability to stay in circulation longer. Researchers investigate it to better understand how modifications in structure influence the stability of peptides and endocrine signaling. Current areas of research include:

• Growth Hormone-Releasing Hormone (GHRH) receptor pharmacology
• Pituitary signaling pathways
• Peptide pharmacokinetics
• Albumin-binding mechanisms
• Long-acting peptide engineering
• Structure-activity relationship studies
• Research pertaining to endocrine signaling
• Molecular stability and peptide disposition

The presence of Drug Affinity Complex (DAC) has made CJC-1295 valuable, particularly in studies investigating how different ways of synthesizing peptides can affect circulation time and interaction with different receptors.

Understanding Albumin Binding Mechanisms

Albumin is the most abundant protein in blood plasma, and one of its primary roles is to transport molecules throughout the body while protecting them from rapid degradation.2 Researchers continue to investigate how DAC enables CJC-1295 to bind to circulating albumin, thereby reducing the rate at which it’s removed from circulation.

GHRH Receptor Activation and Pituitary Signaling Research

This is one of the common areas of study for CJC-1295. One original preclinical study found that albumin-conjugated hGRF analogs retained activity at the GRF receptor in rat models.1 This study set the precedent and made the CJC-1295 peptide useful for examining how structural modifications affect the activity of growth hormone receptors.

Peptide Pharmacokinetics

CJC-1295 provides researchers with a model for studying how amino acid substitutions and albumin conjugation affect peptide absorption, distribution, persistence, and exposure to receptors. The foundational preclinical work focused on molecular design and albumin bioconjugation, while later studies investigated its extended pharmacokinetic and endocrine signaling profile.1,2,4,5 Researchers continue to investigate these areas of study.

CJC-1295 With DAC vs CJC-1295 With No DAC (MOD GRF 1-29)

Important Notice

We supply CJC-1295 DAC peptide exclusively for research. It’s not approved for human or veterinary use. Any discussion concerning the biological activity of CJC-1295 refers to preclinical and in vitro studies only.

References

1. Jetté L, Léger R, Thibaudeau K, et al. Human growth hormone-releasing factor (hGRF) 1–29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052-3058. doi:10.1210/en.2004-1286

2. Belinskaia DA, Voronina PA, Shmurak VI, Jenkins RO, Goncharov NV. Serum albumin in health and disease: esterase, antioxidant, transporting and signaling properties. Int J Mol Sci. 2021;22(19):10318. doi:10.3390/ijms221910318

3. Mayo KE, Godfrey PA, Suhr ST, Kulik DJ, Rahal JO. Growth hormone-releasing hormone: synthesis and signaling. Recent Prog Horm Res. 1995;50:35-73. doi:10.1016/b978-0-12-571150-0.50007-x

4. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. doi:10.1210/jc.2005-1536

5. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-4797. doi:10.1210/jc.2006-1702

At Licensed Peptides™, we focus on quality at every stage of our manufacturing and verification process. Every batch of CJC-1295 follows a strict, pharma-grade workflow, ensuring the peptides you purchase are stable and pure, from synthesis to delivery.

Here’s what sets up apart:

ISO-Certified Cleanroom Manufacturing

We synthesize all our CJC-1295 DAC peptides in sterile, controlled environments to reduce the risk of contamination. This ensures consistency across every single batch.

>99% Verified Purity (HPLC Tested)

In order to verify purity with precision, we use advanced High-Performance Liquid Chromatography (HPLC) analysis. This means your CJC-1295 peptide is free from unwanted chemicals and impurities.

Triple-Verified Identity

We use mass spectrometry to confirm molecular identity. We also test each batch for endotoxins, including lipopolysaccharides (LPS), using Limulus Amebocyte Lysate (LAL). Each batch also undergoes HPLC purity analysis.

Endotoxin-Controlled Production

We supply CJC-1295 with verified endotoxin reports. Low endotoxin levels are important in sensitive receptor-signaling studies where inflammatory contaminants may influence the outcome of the experiment.

Pharma-Grade Raw Materials

Our manufacturing process begins with rigorously tested amino acids and validated reagents. This procedure protects the molecular integrity of the peptide throughout its synthesis.

Lyophilized for Stability

Freeze-dried CJC-1295 DAC is more stable. This means that it’s less likely to degrade during experimentation, because its structural integrity is intact. It also ensures it’s reliable for lab work.

Nitrogen-Sealed Vials

We seal our CJC-1295 peptide in nitrogen to minimize exposure to oxygen and moisture. This preserves its integrity while you’re transporting and storing it.

Made for Serious Research

From peptide synthesis to final fulfillment, we meet the expectations of researchers who need dependable sourcing to ensure they create reproducible studies.

U.S. Based Support

Our responsive U.S.-based team understands the needs of researchers and is available to assist you.

Call us at +1 (855) 322-2214 or email [email protected] to speak with our team.

Research schedules often depend on reliable fulfillment. That’s why Licensed Peptides prioritizes rapid processing and secure shipping throughout the United States.

Same Day Shipping – Orders placed before our daily dispatch cutoff are shipped the same business day whenever products are in stock.

Fast Domestic Delivery – We partner with trusted domestic carriers to provide reliable delivery throughout the United States.

Cold Storage Before Dispatch – Our CJC-1295 remains under controlled storage conditions prior to shipment to help preserve its stability.

Protective Packaging – We package all orders securely to minimize exposure to moisture, temperature fluctuations, and physical damage during transit.

Real-Time Tracking – Tracking information is provided once your order of CJC with DAC ships, allowing you to monitor delivery from dispatch through arrival.

Additional information