LP3-R

LP3-R Overview

LP3-R is a research material used in laboratory studies of receptor interactions and downstream signaling pathways. References to biological activity on this page are provided for research context only and must not be interpreted as claims of therapeutic, diagnostic, or clinical benefit. This product is not offered for human or veterinary use.

LP3-R : Structure

Sequence: YA¹QGTFTSDYSIL²LDKK⁴AQA¹AFIEYLLEGGPSSGAPPPS³
Molecular Formula: C₂₂₁H₃₄₃F₁N₄₆O₇₀
Molecular Weight: 4,731.33 g/mol
PubChem SID: 474492335
CAS Number: 2381089-83-2
Synonyms: LP3-R, LY-3437943, NOP2Y096GV, Triple agonist: GIP / GLP-1 / glucagon receptor agonist

Source:

Coskun et al., 2022 (Cell Metabolism)
Wikipedia – LP3-R (accessed 2025)
Synthachem, 2024; Wikipedia – LP3
PubChem Database
Wikipedia – LP3-R; Chem databases
Jastreboff et al., 2023 (NEJM)

Research Context

In controlled laboratory settings, LP3-R may be used to investigate receptor-binding behavior, signal transduction, and pathway-response modeling. Any references to endocrine or metabolic signaling are limited to experimental research context only and do not imply approved human or animal use.

Research-Grade Purity and Handling Standards

Licensed Peptides supplies research-grade LP3-R for laboratory use only. Products are intended solely for analytical, in vitro, ex vivo, or other controlled research applications. This material is not approved for human or animal use and is not offered as a therapeutic, diagnostic, or clinical product.

Frequently Asked Questions (FAQ)

1. What is LP3-R?

GLP3-R is a laboratory research peptide used to study receptor signaling and peptide behavior in controlled models.

2. What does this page describe?

This page describes research context only. It does not make therapeutic, diagnostic, or clinical claims.

3. Is this product intended for human or animal use?

No. It is supplied strictly for research use only.

4. Does LP3-R affect appetite signaling in research models?

Yes. Research indicates that LP3-R engagement influences central and peripheral appetite-related signaling pathways in experimental settings.

5. How does LP3-R differ from GLP-1-only compounds in studies?

GLP-1-only compounds engage a single pathway, while LP3-R compounds allow simultaneous examination of appetite, glucose regulation, and energy expenditure signaling.

6. Are gastrointestinal effects observed in research?

Some studies report gastrointestinal responses such as delayed gastric signaling, which are commonly documented in peptide research involving GLP pathways.

7. Can LP3-R be used in combination studies?

Yes. Researchers often include LP3-R in multi-compound research designs to explore interaction effects across metabolic systems.

8. Does LP3-R influence metabolic flexibility in studies?

Research observations suggest altered substrate utilization patterns, making it valuable for metabolic flexibility investigations.

9. How long do LP3-R effects persist in research models?

Findings suggest cumulative effects with continued receptor engagement, allowing researchers to study longer-term signaling adaptations.

10. Is LP3-R intended for diagnostic or therapeutic use?

No. LP3-R compounds are for research purposes only and are not intended for diagnostics, treatment, or performance use.

11. Why is LP3-R supplied as an LPS-free peptide?

LP3-R is produced as an LPS-free peptide to reduce the risk of endotoxin-related interference in receptor signaling studies, cellular assays, and biochemical experiments where immune activation could confound experimental data.

12. What does endotoxin-free mean for LP3-R research applications?

An endotoxin-free peptide indicates that LP3-R meets stringent contamination thresholds, supporting reliable outcomes in sensitive in-vitro and ex-vivo research systems that require minimal background inflammatory signaling.

13, Are LP3-R research peptides endotoxin tested?

Yes. Research peptides are endotoxin tested as part of quality assurance protocols to verify compliance with laboratory standards and to support experimental consistency across research applications.

14. How does high purity benefit LP3-R research studies?

High-purity LP3-R reduces variability caused by synthesis by-products or contaminants, allowing clearer interpretation of receptor interactions and signaling behavior within controlled experimental environments.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products available on this website are intended solely for in-vitro research purposes (Latin: “in glass”), meaning they are used in experiments conducted outside a living organism. These products are not medicines or drugs, have not been evaluated or approved by the U.S. Food and Drug Administration (FDA), and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Any administration to humans or animals, whether by ingestion, injection, or other means, is strictly prohibited by law.

As a researcher, you know how important storing peptides correctly is. It preserves their structure and stability. We supply LP3-R in a lyophilized (freeze-dried) form to keep it stable during shipping and while storing.

Understanding Lyophilization

Lyophilization (also called freeze-drying) is a process that removes moisture by freezing peptides and exposing them to low pressure. During this process, water sublimates directly from solid to vapor, resulting in a stable, crystalline white powder.

Researchers often choose to buy lyophilized LP3-R because it tolerates storage conditions well and remains stable longer for long-term studies.

Storage Before Reconstitution

You can store unopened lyophilized LP3-R at room temperature for short periods without compromising peptide quality. In this case, store the vials in a cool, dry environment and protect them from excessive heat, humidity, and direct light.

Short-Term Storage

Refrigeration below 4°C (39°F) supports near-term experimental use. Under these conditions, lyophilized peptides may retain their integrity for several weeks.

Long-Term Storage

Place unopened vials in a freezer. Temperatures of -20°C (-4°F) are commonly used, while -80°C (-112°F) provides an additional margin of protection for long-term preservation and archival storage.

Storage After Reconstitution

Once researchers reconstitute LP3-R with bacteriostatic water, refrigeration becomes essential.

• Store reconstituted solutions below 4°C (39°F)
• Do not freeze-thaw the peptide repeatedly (temperature fluctuations may affect peptide integrity)

Note: Under appropriate laboratory conditions, reconstituted LP3-R solutions may remain suitable for use for up to 30 days.

Why Buy LP3-R Peptide From Us

Here at Licensed Peptides™, we care about quality. That’s why every single batch of LP3-R we supply follows a strict, pharma-grade workflow that ensures the peptides you purchase are stable and pure, from synthesis to delivery.

What Sets Us Apart:

ISO-Certified Cleanroom Manufacturing

We synthesize all our LP3-R peptides in sterile, controlled environments to reduce the risk of contamination. This ensures you get consistency across every single batch.

>99% Verified Purity (HPLC Tested)

In order to verify purity with precision, we use advanced High-Performance Liquid Chromatography (HPLC) methods. This means your peptides are free from unwanted chemicals and impurities.

Triple-Verified Identity

We use mass spectrometry to confirm molecular identity and test each LP3-R batch for endotoxins using Limulus Amebocyte Lysate (LAL). Each LP3-R batch also undergoes HPLC purity analysis.

Endotoxin-Controlled Production

We supply GLP3-R with verified endotoxin reports. Low endotoxin levels are important in sensitive receptor-signaling studies where inflammatory contaminants may influence the outcome of the experiment.

Pharma-Grade Raw Materials

Our manufacturing process begins with rigorously tested amino acids and validated reagents. This procedure protects the molecular integrity of LP3-R throughout peptide synthesis.

Lyophilized for Stability

Freeze-dried LP3-R peptides are more stable, which means they’re less likely to degrade during experimentation, keeping their structural integrity intact. This ensures they’re reliable for lab work.

Nitrogen-Sealed Vials

We seal each LP3-R vial in nitrogen to minimize exposure to oxygen and moisture. This preserves integrity while you’re transporting and storing the peptide.

Made for Serious Research

From peptide synthesis to final fulfillment, we meet the expectations of researchers who need dependable sourcing to ensure they create reproducible studies.

Shipping LP3-R

We understand that timing and product integrity are critical for research.

Same-Day Shipping (USA)

We ship all in-stock orders placed before our daily cutoff the same day within the United States.

Fast Domestic Delivery (1–3 Days)

We use expedited carriers to ensure your LP3-R arrives quickly and reliably nationwide.

Cold Chain Protection

Products are maintained in industrial-grade freezers prior to shipment to support stability and purity.

Secure & Protective Packaging

Each order is carefully packed to reduce exposure to temperature fluctuations, moisture, and physical damage during transit.

Real-Time Tracking

We provide tracking information immediately after shipment so researchers can monitor delivery progress.

Consistency You Can Rely On

No international delays. No customs uncertainty. Just dependable fulfillment from a U.S.-based operation.