BPC157, TB500, GHK-Cu, KPV (Glow Blend)
$149.99
BPC-157: A stable pentadecapeptide originally isolated from gastric juice, BPC-157 is recognized for its ability to stimulate new blood vessel formation, encourage fibroblast migration, and support epithelial repair. These effects are thought to involve modulation of VEGFR2 activity, FAK-paxillin signaling, and nitric oxide pathways. Preclinical studies suggest it promotes the healing of tendons, muscle tissue, and the gastrointestinal tract.
TB-500 (Thymosin Beta-4 fragment): This 43-amino acid peptide regulates actin dynamics, facilitating cellular movement and tissue regeneration. It enhances repair processes by promoting angiogenesis (partly through VEGF upregulation), reducing inflammation, and mobilizing progenitor cells. Evidence indicates it may accelerate recovery in cardiac tissue, dermal layers, and connective structures.
GHK-Cu: A naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) with broad regenerative activity. It has been shown to encourage wound repair, stimulate collagen and extracellular matrix production, and support hair growth. Mechanistically, it influences gene networks involved in tissue remodeling and exerts protective antioxidant and anti-inflammatory actions, partly through TGF-β signaling and regulation of metalloproteinases.
$149.99
$149.99
Peptide Capsules
Purchase Peptides
Purchase Blends
Overview
BPC-157 (Body Protection Compound-157)
Type: Synthetic peptide fragment (15 amino acids) derived from a protective protein in gastric juice.
Mechanisms:
- Promotes angiogenesis (new blood vessel formation) through VEGFR2 signaling.
- Enhances fibroblast migration, collagen production, and tendon-to-bone healing.
- Modulates nitric oxide pathways and reduces inflammatory cytokines.
Potential Uses (research-based):
- Accelerated healing of tendons, ligaments, muscles, and intestinal tissues.
- Possible protective effects on the nervous system and organs under oxidative stress.
TB-500 (Thymosin Beta-4 fragment)
Type: Synthetic version of a peptide fragment from Thymosin Beta-4, a naturally occurring 43-amino acid protein.
Mechanisms:
- Actin-binding and regulation of cytoskeleton dynamics.
- Promotes cell migration, angiogenesis, wound healing, and tissue regeneration.
- Reduces inflammation and fibrosis post-injury.
Potential Uses (research-based):
- Tissue and wound repair, especially in muscle, tendon, and cardiac injury.
- Investigated in eye, skin, and heart recovery models.
GHK-Cu (Copper Peptide Complex, GHK-Cu)
Type: Tripeptide (glycyl-L-histidyl-L-lysine) naturally present in plasma, often studied in its copper-bound form.
Mechanisms:
- Potent signal peptide for wound healing and skin regeneration.
- Stimulates collagen, elastin, glycosaminoglycans production.
- Exhibits antioxidant, anti-inflammatory, and DNA repair-promoting effects.
Potential Uses (research-based):
- Anti-aging and skin repair (widely used in dermatology and cosmetics).
- Hair follicle stimulation and scalp health.
- Tissue healing and protection against oxidative damage.
BPC-157, TB-500, and GHK-Cu are, individually, among the most extensively researched peptides with demonstrated roles in healing and regeneration. Each has been shown to accelerate tissue repair, promote angiogenesis, reduce inflammation, and protect against cellular damage. Beyond these shared effects, each peptide operates through distinct biological pathways, making them complementary rather than redundant. This suggests that combining them may yield synergistic benefits greater than any one peptide alone.
To facilitate exploration of these potential synergies, formulations containing BPC-157 + TB-500 (Thymosin Beta-4 fragment) + GHK-Cu have been developed. Such blends simplify handling, storage, and administration, enabling researchers to focus on outcomes and experimental design without the need to separately manage multiple peptides.
When used together, these peptides may enhance one another’s actions, leading to accelerated wound closure, improved musculoskeletal recovery, and protection against degenerative changes. Future studies examining their combined use in animal models could clarify the extent of these synergistic effects and guide applications in regenerative medicine, dermatology, and tissue repair.
Research
BPC 157, commonly referred to as the “Body Protection Compound,” is a synthetic pentadecapeptide derived from a protein found in human gastric juice. It has shown a wide range of potential therapeutic effects in preclinical studies involving models of various medical conditions, including tissue damage, inflammatory bowel disease, and central nervous system disorders. Unlike many pharmaceutical agents, BPC 157 appears to have a favorable safety profile, with only minimal side effects reported following its use.
Despite its promising results, the compound has yet to receive approval from regulatory bodies like the FDA or other international health authorities, primarily due to a lack of large-scale clinical trials in humans. Notably, in 2022, WADA (World Anti-Doping Agency) placed a temporary ban on BPC 157, although it is no longer included on their current list of prohibited substances.
Interest in BPC 157 continues to grow, especially given its widespread availability through online vendors and its mention in multiple patent applications and issued patents. In this review, we explore the biological properties of BPC 157, emphasizing its mechanisms of action and potential toxicity, which have caught the attention of researchers and medical professionals alike.
GHK-Cu: A Multifunctional Peptide in Regeneration and Repair
GHK (glycyl-L-histidyl-lysine), a naturally occurring peptide found in plasma, saliva, and urine, decreases with age but plays a key role in tissue repair when bound to copper (GHK-Cu). It promotes wound healing by stimulating collagen, glycosaminoglycans, and proteoglycans, while also regulating metalloproteinases and their inhibitors. GHK-Cu restores fibroblast vitality, recruits immune and endothelial cells, and enhances repair in skin, hair follicles, bone, and internal tissues across multiple animal models. In dermatology, it has been shown to tighten skin, improve elasticity and density, reduce wrinkles and photodamage, and address hyperpigmentation. Beyond cosmetic use, GHK-Cu has therapeutic potential in inflammatory skin conditions, chronic lung disease, and certain cancers. Importantly, it influences the expression of thousands of genes, suggesting a broad role in restoring healthier cellular function.
Thymosin Beta-4 and the Quest for Regeneration in Aging
For centuries, humanity has sought ways to counteract aging, yet a definitive solution remains out of reach. While modern medicine has extended lifespan, it has also brought new challenges in addressing age-related decline. Efforts such as stem cell therapies have shown only limited success in restoring full regenerative capacity. An alternative strategy focuses on small, naturally occurring molecules vital in early development. One promising candidate is Thymosin beta-4, a 43–amino acid peptide shown to promote extensive tissue repair, particularly in the heart, through systemic administration. Its regenerative potential suggests that other hidden biological molecules may also serve as powerful tools in slowing or even reversing aspects of aging.
Summary:
There is a vast amount to discuss regarding BPC-157, TB-500, and GHK-Cu, far beyond the scope of a single article. Each peptide has unique contributions to tissue regeneration, inflammation control, and protection against a wide range of health challenges, including cardiovascular injury, infection, and neurodegenerative conditions. While much research highlights their effects individually, the true potential may lie in their combined use.
Of particular significance is their capacity to influence the biology of aging, with evidence suggesting they may help slow or even reverse certain age-related processes. These peptides represent an exciting avenue for extending not only lifespan but also healthspan, emphasizing quality of life alongside longevity. Still, further investigation is needed to fully understand how they work together and how their synergistic actions could enhance healing, disease prevention, and overall wellness.
Scientific Journal & Authors
Dr. Patrycja Kleczkowska, Associate Professor (Ph.D., Eng.), currently serves as Deputy Director for scientific affairs at the Military Institute of Hygiene and Epidemiology. She is also affiliated with the Maria Sklodowska-Curie Medical Academy in Warsaw, where she is involved in teaching and research activities in the field of pharmacology. Between 2005 and 2015, she worked at the Polish Academy of Sciences, focusing on the development and synthesis of biologically active compounds, particularly those with analgesic and neuroprotective properties. At present, her research centers on investigating the toxicity and safety profiles of new biologically active substances with therapeutic potential.
Referenced Citations
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products available on this website are intended solely for in-vitro research purposes (Latin: “in glass”), meaning they are used in experiments conducted outside a living organism. These products are not medicines or drugs, have not been evaluated or approved by the U.S. Food and Drug Administration (FDA), and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Any administration to humans or animals, whether by ingestion, injection, or other means, is strictly prohibited by law.
Test
Storage Instructions:
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
For further information on proper storage techniques, click the link below: