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MK677 Capsules 12. · 5mg
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99%+ HPLC Purity — Independently verified by accredited US laboratory -
Endotoxin-Screened — LAL tested, LPS-free, endotoxin report available
-
GMP-Certified Manufacturing — USA facility, ISO 9001:2015
-
Lyophilized for Stability — Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
4.9 847 verified reviews
MK677 Capsules 12. · 5mg
Total Price
$0.00
Discounted Price
$0.00
Packs
5 packs
You Save
$0.00
0% OFF
Select Strength (mg)
99% HPLC Purity
Select Packs
Bulk pricing applied
📈 Upgrade to 10 vials and save an extra vs. buying 5 — nearly 3 free vials.
Select Purchase Option:
-
99%+ HPLC Purity —
Independently verified by accredited US laboratory
-
Endotoxin-Screened —
LAL tested, LPS-free, endotoxin report available
-
GMP-Certified Manufacturing —
USA facility, ISO 9001:2015
-
Lyophilized for Stability —
Shipped cold-packed, intact for reconstitution
Molecular Weight
Third Party Tested
APPLICATION
For Research Use only
Form
Lyophilized Powder
Storage
-20°C Long Term
Purity (HPLC)
99%+ Third Party Verified
Manufacture
USA / GMP
60 Capsules
MK-677 Capsules 12.5mg are supplied strictly for laboratory research use only. This material is intended for analytical and controlled research applications. It is not approved or intended for human or animal use, ingestion, dosing, or therapy.
MK677 at a glance
| Form supplied | Capsules |
|---|---|
| Application | Research use only |
What is MK677?
MK-677 (Ibutamoren): A Selective Ghrelin Receptor Agonist
MK-677 Capsules 12.5mg are supplied strictly for laboratory research use only. This material is intended for analytical and controlled research applications. It is not approved or intended for human or animal use, ingestion, dosing, or therapy.
Important:
This compound is supplied strictly for laboratory research, analytical testing, and development purposes.
It is not approved for human consumption.
MK-677 (ibutamoren) is not a peptide but a small-molecule, orally active spiroindane peptidomimetic. It was designed to reproduce the receptor interaction of the peptide growth hormone secretagogues in a non-peptide scaffold, which is what gives it oral bioavailability.1
Why is MK677 studied?
It is studied as the orally active reference compound for the growth hormone secretagogue receptor. Because it is a stable small molecule rather than a peptide, it is the standard positive control when peptide secretagogues are compared, and it does not share their solution-stability limitations.2
How is MK677 studied in the lab?
The published characterisation used rat and dog pituitary preparations for receptor activity and oral administration studies in those species, with plasma growth hormone and IGF-I as the primary endpoints.1, 2
What has preclinical research reported?
Research Context
MK-677 may be used in laboratory settings to study receptor interaction, signaling pathways, and experimental assay responses. Any references to biological activity are provided for research context only and must not be interpreted as claims of safety, efficacy, or intended human use.
Why Researchers Study MK-677
MK-677 continues to be investigated in academic and laboratory settings for its role in:
- GH/IGF-1 axis modulation
- Age-related endocrine decline models
- Sleep architecture research
- Bone density and metabolic pathway analysis
Its oral format differentiates it from peptide-based secretagogues in experimental frameworks.
Scientific Characteristics
- Compound Name: Ibutamoren Mesylate
- Molecular Classification: Growth Hormone Secretagogue
- Target Receptor: GHS-R1a (Ghrelin Receptor)
- Mechanism: Endogenous GH stimulation
- Research Interest Areas: Endocrinology, Metabolism, Longevity Science
Preclinical Findings
Published preclinical literature has examined:
- GH secretion dynamics in experimental models
- IGF-1 readouts in experimental models
- Pharmacodynamic profile relative to other GH secretagogue formats
For full study references, review NIH-indexed publications on MK-677 / Ibutamoren in endocrine research.
Quality & Compliance Standards
- Manufactured in GMP-aligned facilities
- Third-party purity testing
- Batch-level verification
- Certificate of Analysis (COA) available
- Secure, compliant fulfillment
All products are intended exclusively for laboratory research and development use.
Regulatory & Safety Notice
This product:
- Has not been evaluated by the FDA
- Is not intended to diagnose, treat, cure, or prevent any disease
- Is not a dietary supplement
- Is not for human consumption
- Is not a compounding pharmacy product
- Is supplied as a chemical research material
Who We Serve
- Research laboratories
- Academic institutions
- Biotechnology developers
- Analytical testing facilities
- Pharmaceutical R&D teams
Order MK-677 – Research Grade
High-purity MK-677 capsules formulated for laboratory handling and research protocols.
✔ Verified purity
✔ Batch-tested
✔ COA provided
✔ Discreet shipping
Request Batch Documentation or Place Research Order
Peptidomimetic design (in vitro and animal)
L-163,191 was reported as a potent, orally active growth hormone secretagogue in pituitary cell assays and in animal work, establishing the non-peptide scaffold for this class.1
Secretagogue receptor pharmacology
Review work describes how peptidomimetic secretagogues act through a receptor distinct from the growth-hormone-releasing-hormone receptor, which is the mechanistic reason the two classes are studied side by side.2
References
- Patchett AA, Nargund RP, Tata JR, et al. Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue. Proc Natl Acad Sci U S A. 1995;92(15):7001-7005. doi:10.1073/pnas.92.15.7001
- Smith RG, Van der Ploeg LHT, Howard AD, et al. Peptidomimetic regulation of growth hormone secretion. Endocr Rev. 1997;18(5):621-645. doi:10.1210/edrv.18.5.0316
For laboratory research use only. Products on this website are intended solely for in-vitro research. They are not medicines, have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease. Any administration to humans or animals is strictly prohibited.
What are these peptides made for?
Our peptides are produced exclusively for laboratory and scientific research purposes.
Licensed Peptides™ products are developed using industry-standard synthesis and purification protocols, making them suitable for in vitro research, analytical testing, and experimental models.
Research-grade standards
- Synthesized via Solid Phase Peptide Synthesis (SPPS)
- Purified using advanced HPLC methods
- Verified through analytical quality control processes
- Screened for heavy metals and endotoxins
Consistency across batches
Strict process controls ensure reproducibility, allowing researchers to work with confidence across experiments.
Applications
Our peptides are commonly used in research involving:
- Cellular signaling pathways
- Tissue remodeling and repair mechanisms
- Extracellular matrix regulation
- Molecular biology and biochemical studies
All products are intended for research use only and are not for human or animal consumption, therapeutic use, or clinical application.
Why buy from Licensed Peptides
At Licensed Peptides™, quality isn’t a claim — it’s a controlled, repeatable process.
Every peptide we produce follows a strict, pharma-grade workflow designed to ensure purity, stability, and consistency from synthesis to delivery.
What sets us apart
ISO-certified cleanroom manufacturing
All peptides are synthesized in sterile, controlled environments to eliminate contamination risk and ensure batch consistency.
>99% verified purity (HPLC tested)
We use advanced High-Performance Liquid Chromatography (HPLC) to separate and verify peptide purity with precision.
Comprehensive safety testing
Each batch undergoes heavy metal and endotoxin screening to ensure it is free from hidden contaminants.
Pharma-grade raw materials
We start with rigorously tested amino acids and reagents, ensuring integrity at the molecular level.
Lyophilized for stability
Freeze-dried peptides maintain long-term stability, potency, and reliability for research applications.
Nitrogen-sealed vials
Every vial is protected from oxygen and moisture, preserving structural integrity during storage and transit.
Built for serious research
From synthesis to delivery, every step is engineered to meet the expectations of professionals who require accuracy, consistency, and reliability.
For laboratory research use only. Not for human or veterinary use.
How orders ship
We understand that timing and product integrity are critical for research.
| Ships to | United States (including minor outlying islands) |
|---|---|
| Processing days | Monday to Friday, excluding holidays |
| Daily cut-off | Paid orders placed before 4:00 PM PST are typically shipped the same business day |
| Free shipping | FedEx 2-Day Express on orders over $200 and for VIP members |
| Standard | USPS Ground Advantage, 3–7 business days (not guaranteed) — $8.95 |
| Expedited | FedEx 2-Day $11.95 · UPS 2-Day $19.95 · FedEx Next Day $44.99 |
| Signature | Required on delivery for orders of $1,000 or more |
How orders are handled
Cold chain protection
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity.
Secure & protective packaging
Each order is carefully packed to protect against temperature fluctuations, moisture exposure, and physical damage during transit.
Tracking
Once your order has shipped you will receive a tracking number by email, so you can monitor delivery progress.
Shipped from the United States
Orders are dispatched domestically from a U.S.-based operation, so there are no international customs steps.
Delivery times
Shipping times are estimates and begin after order processing. Delays may occur due to carrier issues, weather, or other unforeseen factors, and delivery dates are not guaranteed. Full terms are in our Shipping & Delivery Policy.
For laboratory research use only. Not for human or veterinary use.
Additional information
| pack | 1 pack, 3 pack, 5 pack, 10 pack |
|---|
Storage
Store sealed in original packaging in a cool, dry place away from light. Do not ingest, inject, reconstitute, or otherwise administer.
99%+ — Passes ≥99% 
Download Full COA / HPLC Report (PDF) 
99%+ Every Batch
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